Headache Beyond the Brain

Peripheral Trigeminal Input, Ocular Surface Dysfunction, and the Sensory Load Model in Chronic Headache Version 1.0 Publication Date: March 2026 Athens – Greece WOD.global – World Organization of Dermophthalmology Abstract Introduction Headache is one of the most prevalent and disabling neurological symptoms worldwide. Despite major advances in neuroimaging and in the neurovascular understanding […]
From Isolated Ophthalmic Entities to the Pathological Spectrum

EXECUTIVE SUMMARY Classical Ophthalmology relies on binary diagnostic models that inadequately describe the temporal and functional evolution of disease. Many ocular “conditions” represent stages within a continuous pathological spectrum (continuum), not independent entities. Blepharitis, MGD, dry eye disease, and chalazion are different expressions along the same pathological trajectory. Disease does not “reside” solely within the […]
Defining the Eye–Skin Axis as an Emerging Interdisciplinary Field

A White Paper by the World Organization of Dermophthalmology (WOD)Conceived in Greece — Applied Worldwide Executive Summary Modern medicine has achieved remarkable advances through specialization. However, this necessary fragmentation has also created clinically relevant gaps—areas of the human body that do not fully belong to a single discipline and therefore remain insufficiently addressed. One such […]
Ophthalmoderma – The New Target Organ in Dermophthalmology

Position Paper of the World Organization of Dermophthalmology (WOD) Abstract Classical Anatomy and Physiology have traditionally treated organs as separate structures with clear boundaries: eye, skin, hair, mucosa.The zones where these systems meet – the interfaces – were viewed merely as “transitional areas” between organs, not as autonomous biological systems.Dermophthalmology introduces the concept of Ophthalmoderma as a […]